首页> 外国专利> CELL WITH REDUCED OR DELETED ACTIVITY OF A PROTEIN INVOLVED IN GDP FUCOSET TRANSPORT

CELL WITH REDUCED OR DELETED ACTIVITY OF A PROTEIN INVOLVED IN GDP FUCOSET TRANSPORT

机译:GDP烟碱转运涉及蛋白质活性降低或降低的细胞

摘要

A cell in which the activity of a protein relating to transport of an intracellular sugar nucleotide, GDP-fucose, to the Golgi body is more decreased or deleted than its parent cell; a process for producing an antibody composition using the cell; a transgenic non-human animal or plant or the progenies thereof, in which genome is modified so as to have a decreased or deleted activity of a protein relating to transport of an intracellular sugar nucleotide, GDP-fucose, to the Golgi body; a process for producing an antibody composition from the animal or plant; and a medicament comprising the antibody composition.
机译:一种细胞,其蛋白的活性与胞内糖核苷酸GDP-岩藻糖向高尔基体的运输有关,比其亲本细胞更多地减少或缺失;使用该细胞生产抗体组合物的方法;转基因的非人类动物或植物或其后代,其中的基因组经过修饰,使蛋白质的活性降低或缺失,该活性与细胞内糖核苷酸GDP-岩藻糖向高尔基体的运输有关;从动物或植物生产抗体组合物的方法;以及包含所述抗体组合物的药物。

著录项

  • 公开/公告号AT503829T

    专利类型

  • 公开/公告日2011-04-15

    原文格式PDF

  • 申请/专利权人 KYOWA HAKKO KIRIN CO. LTD.;

    申请/专利号AT20030720896T

  • 发明设计人 KANDA YUTAKA;SATOH MITSUO;MORI KATSUHIRO;

    申请日2003-04-09

  • 分类号C12N5/10;A61P9;A61P29;A61P31;A61P35;A61P37;C07K14/47;C07K16/18;C07K16/28;C12N15/113;C12N15/82;C12P21/08;

  • 国家 AT

  • 入库时间 2022-08-21 18:03:26

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