USE OF ANTI-TNF OR ANTI-IL1 RNAI TO SUPPRESS THE EFFECT OF INFLAMMATORY CYTOKINS FOR LOCAL PAIN TREATMENT

摘要

Disclosed herein are methods and sequences used to treat pain. Specifically, the methods and sequences include locally administering nucleic acid molecules that suppress the expression of amino acid sequences that encode for pro-inflammatory cytokines and their receptors to treat acute or neuropathic pain associated with sciatica.