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MELANOMA ASSOCIATED ANTIGENIC POLYPEPTIDE, EPITOPES THEREOF AND VACCINES AGAINST MELANOMA
MELANOMA ASSOCIATED ANTIGENIC POLYPEPTIDE, EPITOPES THEREOF AND VACCINES AGAINST MELANOMA
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机译:黑色素相关的抗原多肽,其表位和针对黑色素的疫苗
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摘要
The present invention describes a melanoma associated antigen known as gp100. Furthermore, peptides derived form said antigen are claimed. Gp100 and its peptides can be used in vaccines for the treatment of melanoma. Another aspect of the invention are host cells capable of expression of gp100 or the gp100-derived peptides. Furthermor, tumor infiltrating lymphocytes (TIL's) specifically recognizing gp100 are claimed, as are vaccines with these TIL's. Furthermore, diagnostics for the detection of melanoma and for the monitoring of vaccination form part of the invention.
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