首页> 外国专利> RECOMBINANT PROTEIN OF FIBROBLAST GROWTH FACTOR HAVING ADHESIVE ACTIVITY FOR STEM CELLS AND METHOD FOR CULTURING STEM CELLS USING THE SAME

RECOMBINANT PROTEIN OF FIBROBLAST GROWTH FACTOR HAVING ADHESIVE ACTIVITY FOR STEM CELLS AND METHOD FOR CULTURING STEM CELLS USING THE SAME

机译:具有干细胞粘附活性的成纤维细胞生长因子重组蛋白及使用该细胞培养干细胞的方法

摘要

The present invention relates to a recombinant protein of a fibroblast growth factor (FGF) having an adhesive activity for stem cells and a method for culturing stem cells using the same. More particularly, the present invention relates to a recombinant protein having an adhesive activity for stem cells by fusion of a polypeptide linker at amino terminal of FGF, and a method for culturing stem cells using immobilized FGF comprising: fixing the recombinant protein in a culture vessel with a hydrophobic surface using amino terminal of the polypeptide linker, adhering stem cells on the recombinant protein-fixed culture vessel, and culturing the stem cells.
机译:本发明涉及对干细胞具有粘附活性的成纤维细胞生长因子(FGF)重组蛋白,以及使用该重组蛋白培养干细胞的方法。更具体地,本发明涉及通过在FGF的氨基末端融合多肽接头而对干细胞具有粘附活性的重组蛋白,以及使用固定的FGF培养干细胞的方法,该方法包括:将重组蛋白固定在培养容器中。通过使用多肽接头的氨基末端在疏水表面上形成疏水性表面,将干细胞粘附在重组蛋白固定的培养容器上,并培养干细胞。

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