HOLLOW FIBER MEMBRANE WITH EXCELLENT PERFORMANCE STABILITY AND BLOOD PURIFIER AND METHOD FOR PRODUCING HOLLOW FIBER MEMBRANE

摘要

Purpose: To provide a blood purifier having a high water permeability, for use in treatment of chronic renal failure, which is not variable in performance during the treatment, independently of a patient's body condition.; Solution: The present invention provides a hollow fiber membrane excellent in performance stability, which has an average thickness of from 10 to 50 µm and an average pore radius of from 150 to 300 Å, and which shows a pure water permeability of 150 to 1,500 mL/m²/hr./mmHg at 37°C, characterized in that the ratio of the overall mass transfer coefficient (Koβ2) of a blood plasma solution of β2-microgloburin to the overall mass transfer coefficient (Komyo) of an aqueous myoglobin solution (i.e., Koβ2/Komyo) is from 0.7 to 1.0.