NON-FRAGMENTING LOW FRICTION BIOACTIVE ABSORBABLE COILS FOR BRAIN ANEURYSM THERAPY
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机译:用于脑动脉瘤治疗的无碎片低摩擦生物活性可吸收线圈
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摘要
Non-fragmenting low friction bioactive absorbable coils are disclosed that improve long-term anatomic results in the endo vascular treatment of intracranial aneurysms. The coils are composed of at least one biocompatible and bioabsorbable polymer. The coils are then coated with a polymer to reduce the friction. The coating can contain drugs, such as growth factors, and can be used to accelerate histopathologic transformation in aneurysms. The coil can be a polymer such as polyglycolic acid (PGA), poly-L-lactic acid (PLLA), polycaprolactive, poly-L-lactide, polydioxanone, polycarbonates, polyanhydrides, polyglycolic acid/poly-L-lactic acid copolymers, polyhydroxybutyrate/hydroxyvalerate copolymers, or combinations thereof.
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