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METHODS FOR DETECTING IgH/BCL-1 CHROMOSOMAL TRANSLOCATION
METHODS FOR DETECTING IgH/BCL-1 CHROMOSOMAL TRANSLOCATION
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机译:检测IgH / BCL-1染色体转运的方法
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摘要
The invention provides methods for detection of Bcl-1 nucleic acid in acellular body fluid. The methods can be used to detect the IgH/Bcl-1 translocations (11;14)(q13;q32) in acellular body fluid. The chromosomal translocation (11;14)(q13;q32) is often associated with mantle cell (centrocytic) lymphoma and occasionally in other B-cell neoplasms, notably myeloma. The invention is useful in the diagnosis of mantle cell lymphoma (MCL) and also for determining the prognosis of the disease.
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