NOVEL PEPTIDES UPREGULATING BDNF EXPRESSION AND PHARMACEUTICAL COMPOSITION FOR PROTECTION AND THERAPY AGAINST ALZHEIMER'S DISEASE AND PARKINSON'S DISEASE COMPRISING THE SAME

摘要

PURPOSE: A peptide which enhances BDNF protein expression in a human dopamine reactive cell line is provided to prevent and treat various neural diseases. CONSTITUTION: A peptide which enhances BDNF protein expression is denoted by N'-(Z1)alpha-Z2-(Z3)beta-C'. The peptide increases BDNF protein expression in human dopamine reactive cell line. A pharmaceutical composition for preventing and treating Alzheimer's disease, Parkinson's disease, chromic stress depression, stroke, Huntington disease, dementia, obesity, or diabetic neuropathy.