A method for constructing a patterned slides for protein chip and protein chip sensors consisting of biomarkers to assess anti-obesity activity using the same and use thereof

摘要

The present invention is a sensor for protein biomarker protein chip chip patterned substrate and anti-obesity activity assessment using the same The production method and relates to the use, in the protein chip board manufacturing, depositing an amine group to a specific area, the remaining area is to be immobilized to a protein on certain areas of the substrate to exhibit hydrophobic bleeding effect is significantly decreased patterned There is an excellent effect of providing a substrate. In addition, the present invention has the excellent effect of providing the pattern on the screen substrate obesity biomarker antibody and protein sensor chip by fixing the cross-linker to evaluate the activity of anti-obesity drugs or food materials. A patterned substrate of the present invention not only has the effect of enabling the mass analysis of the protein's activity to integrate up to tens of thousands of proteins, this protein chip using the patterned substrate is required for the analysis of the sample as compared to the prior art there is an effect that can significantly reduce the amount.