Preparation method of silica capillary column and silica capillary column obtained thereby

摘要

The present invention includes an imprint molecule, especially acid template molecule (acidic template) or carboxyl groups on the inner wall of silica capillaries imprinted polymer for the template molecule using a molecule (molecule imprinted polymer, MIP) relates to a production method of the open structure type molecular imprinted polymer to form a porous silica thin film of the capillary column, reducing the cost of production the production process is simplified, the production reproducibility incomparable you can, and to facilitate cleaning of the mold is removed by forming a molecule having a porous structure with a bumpy surface, but it can dramatically solve the problem of persistence and continuous outflow (bleeding) in the general shortcomings of the molecule as a template molecule imprinted polymer but, since the molecular recognition performance is very good and bumpy surface and the chromatographic mass transfer resistance due to the porous structure dramatically reduced by achiral and chiral separation exhibited excellent performance in a separate resolution, new capillary electrophoresis chromatography can be used as a column.