water-soluble conjugated polymer compound, its preparation method and electrostatic self-assembly of proteins using a biosensor pattern

摘要

This invention is a sulfonate, a carboxylic acid ammonium salt or the introduction of the ionic groups which properties are soluble in water relates to a water-soluble conjugated polymers and a method for having the biosensor. In addition, the present invention certain biomaterials, especially protein or DNA and selectively introducing a linker capable of binding ( ) to interact with the solution to obtain a fluorescent dye is labeled at the terminal of the specific bio-substance soluble conjugated polymer ( ) protein or DNA, as well as on the detection of, and preparation of the polymers in the electrostatic self-assembled thin film ( ) and on the detection method using the multi-selective fluorescent protein or DNA pattern. ; in accordance with the present invention water-soluble conjugated polymer is protein-ligand, as well as detection of a specific bio-material in an aqueous solution by the interaction, through a pattern even on a specific biomaterial to form a thin film detection is possible. In particular, certain biomaterials in solid-ligand interaction using a high selectivity for a particular biomaterial and allows for multiple fluorescent pattern using the fluorescence resonance energy transfer, it can be used as a biosensor based on