NOVEL QUINOLINE DERIVATIVES, SYNTHESIS METHOD THEREOF, USE THEREOF IN TREATING MYCOBACTERIAL INFECTIONS, PHARMACEUTICAL COMPOSITION BASED ON SAID DERIVATIVES

摘要

FIELD: chemistry.;SUBSTANCE: invention relates to novel quinoline derivatives of general formula II, where R¹ denotes halogen, R² denotes halogen, R³ denotes hydroxy, R⁴, R⁵ denote C₁-C₃-alkyl, R⁶ denotes aryl, R⁷ denotes aryl, n=1 or 2, as well as to pharmaceutically acceptable acid or base addition salts thereof, having activity towards mycobacteria. The invention also relates to a method for synthesis of formula II compounds.;EFFECT: obtaining novel quinoline derivatives with useful biological activity.;3 cl, 4 tbl, 5 ex