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Combination, to treat e.g. tumors e.g. breast cancer, and psoriasis comprises substituted N-(4-hydrosulfonimidoylphenyl)-5-(trifluoromethyl)pyrimidin-2-amine compounds and antihyperproliferative, cytostatic or cytotoxic substances
Combination, to treat e.g. tumors e.g. breast cancer, and psoriasis comprises substituted N-(4-hydrosulfonimidoylphenyl)-5-(trifluoromethyl)pyrimidin-2-amine compounds and antihyperproliferative, cytostatic or cytotoxic substances
Combination comprises substituted N-(4-hydrosulfonimidoylphenyl)-5-(trifluoromethyl)pyrimidin-2-amine compounds (I) and their salts, diastereomers and enantiomers and antihyperproliferative, cytostatic or cytotoxic substances. Combination comprises substituted N-(4-hydrosulfonimidoylphenyl)-5-(trifluoromethyl)pyrimidin-2-amine compounds of formula (I) and their salts, diastereomers and enantiomers and antihyperproliferative, cytostatic or cytotoxic substances. X : -O- or -NH-; R1 : methyl, ethyl, propyl or isopropyl; R2, R3 : H, methyl or ethyl; and R4 : 1-6C-alkyl or 3-7C-cycloalkyl ring. [Image] ACTIVITY : Cytostatic; Antipsoriatic; Vulnerary. MECHANISM OF ACTION : Pan-cyclin dependent kinase (CDK) inhibitor.
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机译：组合物包括取代的N-（4-氢磺酰亚胺基苯基）-5-（三氟甲基）嘧啶-2-胺化合物（I）及其盐，非对映异构体和对映异构体以及抗过度增殖，抑制细胞生长或细胞毒性的物质。组合物包含式（I）的取代的N-（4-氢磺酰亚胺基苯基）-5-（三氟甲基）嘧啶-2-胺化合物及其盐，非对映异构体和对映异构体以及抗过度增殖，抑制细胞生长或细胞毒性的物质。 X：-O-或-NH-; R1：甲基，乙基，丙基或异丙基; R 2，R 3：H，甲基或乙基; R 4：1-6C-烷基或3-7C-环烷基环。 [图像]活动：细胞抑制作用;对牛皮癣;伤药。作用机理：泛细胞周期蛋白依赖性激酶（CDK）抑制剂。
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