ANTIBODY FOR ASSAYING ADAMTS13 ACTIVITY AND METHOD FOR ASSAYING THE ACTIVITY

摘要

PROBLEM TO BE SOLVED: To provide a useful antibody for measuring activity of von Willebrand factor (VWF) nicking enzyme (ADAMTS13), in particular, a monoclonal antibody and a method for measuring ADAMTS13 activity.;SOLUTION: There are provided a monoclonal antibody which has specific reactivity to an antigenic determinant site having a specific amino acid sequence, but has no specific reactivity to the complete VWF molecule, produced by reacting ADAMTS13 with VWF that is a substrate or a partial peptide of VWF that is a potential substrate, and a method for measuring ADAMTS13 activity using the antibody.;COPYRIGHT: (C)2012,JPO&INPIT