Derivatives of pyrazolo 1,5-a pyridine useful in the treatment of CNS diseases and cancers, Pharmaceutical compositions containing them and favorable Synthesis.

摘要

Compounds of formula (1), in which R represents a hydrogen Atom or a Halogen or alkyl group C1 - 6; X represents one or more substituents selected from a hydrogen or Halogen Atom, an alkyl group halogenoalquilo C1 C1 - 6 - 6, 6 - alkoxy halogenoalcoxi C1, C1 - 6 Ciano, Hydroxy or Hidroxialquilo C1 - 6; and represents a hydrogen Atom,Halogen or alkyl group C1 - 6; r1 represents a group or nr2r3 or4; R2 and R3 independently represent a hydrogen Atom, an alkyl group hidroxialquilo C1 C1 - 6 - 6 or - 6 or oxoalquilo C1, R2 and R3 are the nitrogen Atom which carries a opcionalmen heterocycle You substituted with an alkyl group C1 - 6 Hydroxy and oxo; R4 represents an alkyl group C1 - 6Hidroxialquilo C1 - 6 or in the form of Base or acid Addition Salt of a C1 - 6, in the form of a base or an Acid Addition Salt.