首页> 外国专利> Derivatives of azabiciclo 3.2.0 hept-3-ene - 6ilo, Preparation method of same, Synthesis Intermediates, Pharmaceutical compositions containing them and Use thereof for the treatment of Neurodegenerative Diseases such as Alzheimer's disease.

Derivatives of azabiciclo 3.2.0 hept-3-ene - 6ilo, Preparation method of same, Synthesis Intermediates, Pharmaceutical compositions containing them and Use thereof for the treatment of Neurodegenerative Diseases such as Alzheimer's disease.

机译:杜鹃花[3.2.0]庚-3-烯-6ilo的衍生物,其制备方法,合成中间体,含有它们的药物组合物及其在治疗神经退行性疾病例如阿尔茨海默氏病中的用途。

摘要

Claim 1: compounds of formula (1) in which ALK represents a Chain alquileno, W represents a Group - N (R) - C (= o) - R or - C (= o) n (R) r in R and R 'are, independently of one another. A Hydrogen Atom, an alkyl group or linear or branched C1 - 6 replaced opcionalment And with one or More groups selected from Halogen, Hydroxy and alkoxy,Understanding that the term alquileno designates a Bivalent radical, linear or branched, contains from 2 to 6 carbon ATOMS, the term designates a Oxy alkyl alkoxy group whose linear or branched alkyl Chain, containing 1 to 6 carbon ATOMS, its enantiomers and Diastereomers. And their Addition salts with a pharmaceutically acceptable acid or a base.
机译:权利要求1:式(1)的化合物,其中ALK代表链alquileno,W代表R和R中的基团-N(R)-C(= o)-R或-C(= o)n(R)r是彼此独立的。氢原子,烷基,直链或支链的C1-6取代的取代基,并具有一个或多个选自卤素,羟基和烷氧基的基团,但术语“ alquileno”表示直链或支链的二价基团,含有2至6个碳ATOMS,该术语表示其直链或支链烷基链的含1至6个碳的ATOMS,其对映异构体和非对映异构体的氧基烷基烷氧基。及其加成盐与药学上可接受的酸或碱。

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