METHODS FOR TREATING A TUMOR, FOR TREATING A PATHOLOGICAL CONDITION ASSOCIATED WITH ANGIOGENESIS, TO STIMULATING ENDOTHELIAL CELL PROLIFERATION, TO REDUCE OR INHIBIT ENDOTHELIAL CELL DIFFERENTIATION, TO REDUCE OR INHIBIT TO DEVELOP, DETERMINING, DETECTING EFFECTIVENESS OF AN ANTI-ANGIOGENIC AGENT, USES OF A DLL4 ANTAGONIST AND USE OF A DLL4 AGONISTER

摘要

METHODS FOR TREATING A TUMOR, FOR TREATING A PATHOLOGICAL CONDITION ASSOCIATED WITH ANGIOGENESIS, TO STIMULATING ENDOTHELIAL CELL PROLIFERATION, TO REDUCE OR INHIBIT, DETERMINING, INHIBITING, DETERMINING, INHIBITING, DETERMINING, DETERMINING, DETERMINING THE EFFECTIVENESS OF AN ANTI-ANGIOGENIC AGENT, USES OF A DLL4 ANTAGONIST AND USE OF A DLL4 AGONIST The present invention provides methods of using a DLL4 modulator to modulate vascular development. In addition, treatment methods that use DLL4 modulators, such as DLL4 antagonists, are provided.