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NEW KINASE-HEMMER

机译：新激酶-悍马

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摘要

The present invention provides compounds of formula (I), and pharmaceutically acceptable salts thereof. The formula (I) compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula (I) compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

机译：本发明提供式（I）化合物及其药学上可接受的盐。式（I）化合物抑制生长因子受体如VEGFR-2和FGFR-1的酪氨酸激酶活性，从而使其可用作抗癌剂。式（I）化合物也可用于治疗与通过生长因子受体起作用的信号转导途径有关的其他疾病。

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公开/公告号AT537843T

专利类型
公开/公告日2012-01-15

原文格式PDF
申请/专利权人 BRISTOL-MYERS SQUIBB COMPANY;
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申请/专利号AT20030765881T
发明设计人 BHIDE RAJEEV;CAI ZHEN-WEI;QIAN LIGANG;BARBOSA STEPHANIE;LOMBARDO LOUIS;ROBL JEFFREY;
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申请日2003-07-18
分类号A61K31/53;A61K45/06;A61K31/5377;A61K31/541;A61K31/662;A61K45;A61P1/04;A61P1/16;A61P3/04;A61P3/10;A61P7/06;A61P9;A61P9/06;A61P9/08;A61P9/10;A61P11;A61P11/06;A61P13/08;A61P13/10;A61P13/12;A61P15;A61P17;A61P17/02;A61P17/06;A61P19;A61P19/02;A61P19/10;A61P21/04;A61P25;A61P25/02;A61P25/16;A61P25/28;A61P27/02;A61P27/16;A61P29;A61P31/10;A61P31/12;A61P31/18;A61P31/22;A61P35;A61P35/02;A61P35/04;A61P37;A61P37/02;A61P37/04;A61P37/06;A61P43;C07D487/02;C07D487/04;C07F9/6561;
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入库时间 2022-08-21 17:21:48

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