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analysis of biological zielmoleku00fclen using a fluoreszenzmarker load-bearing biochips

机译:使用荧光标记载体的生物芯片对生物学Zielmolek进行分析

摘要

Analytical support (A), which is fixed to a carrier, comprises many oligonucleotides (ON), each of which is labeled by a fluorescent compound (I), the fluorescence of which varies when ON hybridizes to its complement, is new. Independent claims are also included for the following: (1) the quality control of (A) in which the amounts and positions of the fixed ONs are determined by measuring the fluorescence from (I); an (2) analyzing biological targets by applying them to (A) and identifying those ON which have hybridized by measuring fluorescence from each ON before and after contact with the targets.
机译:固定在载体上的分析支持物(A)是许多寡核苷酸(ON),其中每个寡核苷酸都被荧光化合物(I)标记,当ON与其互补序列杂交时,其荧光会发生变化。还包括以下方面的独立权利要求:(1)(A)的质量控制,其中通过测量(I)的荧光来确定固定ON的数量和位置; (2)通过将生物靶标应用于(A)来分析生物靶标,并通过测量与靶标接触之前和之后每个ON的荧光来鉴定已杂交的ON。

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