COMPOSITIONS FOR USE IN TREATING OR PREVENTING CANCER, BREAST CANCER, LUNG CANCER, OVARIAN CANCER, METASTASIS, HEART FAILURE, CARDIAC REMODELLING, DILATED CARDIOMYOPATHY, AUTOIMMUNE DISEASES, OR DISEASES OR DISORDERS RELATED THERETO

摘要

The present invention relates to compositions comprising an inhibitor of a polynucleotide, said polynucleotide to be inhibited being capable of decreasing or suppressing expression of Dicer or a biologically active derivative thereof for use in treating or preventing cancer, metastasis, heart failure, cardiac remodelling, dilated cardiomyopathy, autoimmune diseases, or diseases or disorders related thereto. Furthermore, the present invention also relates to methods of treating or preventing cancer, metastasis, heart failure, cardiac remodelling, dilated cardiomyopathy, autoimmune diseases, or diseases or disorders related thereto.