HBcAg expression and diagnostic and therapeutic uses

摘要

The invention concerns an expression cassette which is functional in a cell derived from a yeast selected from the group consisting of strain Pichia and Schizosaccharomyces, allowing the expression of HBc DNA or fragments thereof encoding HBcAg or fragments thereof, placed under the control of the elements necessary for its expression; a process for the detection of anti-HBc antibodies or HBcAg protein in a biological sample.