GENETIC MARKERS SPECIFIC FOR CLOSTRIDIUM DIFFICILE RIBOTYPES 027 (NAP01/B1; RT 027) AND 078 (NAP7/8; RT 078) AND THEIR USE

摘要

The present invention relates to biomarkers unique to a Clostridium difficile hypervirulent ribotypes 027 and 078; a method for detecting, distinguishing, identifying and/or isolating and/or classifying a Clostridium difficile hypervirulent/toxigenic strain using such biomarkers in a sample or product. Primers, probes and kits for detecting Clostridium difficile (hyper) virulent strains, more in particular ribotypes 078 and 027 like (associated) strains are further provided by the invention.