首页> 外国专利> SOLID SUBSTRATE STRUCTURE FOR PEPTIDE SYNTHESIS USING A SOLID PHASE SYSTHESIS AND A MANUFACTURING METHOD OF THE SOLID SUBSTRATE STRUCTURES

SOLID SUBSTRATE STRUCTURE FOR PEPTIDE SYNTHESIS USING A SOLID PHASE SYSTHESIS AND A MANUFACTURING METHOD OF THE SOLID SUBSTRATE STRUCTURES

机译:固相合成的肽合成用固体基质结构及其制备方法

摘要

PURPOSE: A solid substrate structure for peptide synthesis using a solid phase synthesis and a manufacturing method of the solid substrate structures are provided to synthesize peptide even in the solid phase which is vulnerable under an organic solvent environment required for the reaction.;CONSTITUTION: A solid substrate structure for peptide synthesis using a solid phase synthesis includes A parlylene thin film in which a solid state substrate parent for the peptide synthesis and amine radical derivative are formed. The solid state substrate structure has a structure in which the parylene N thin film is evaporated on the solid state substrate parent and solid state substrate parent, and the parlylene A thin film is the evaporated on the parylene N thin film. The parylene N thin film has the thickness of 300 nano meters or greater and 1 micro meter or less. The solid state substrate structure has a structure in which the parlylene a thin film is evaporated on the solid state substrate parent and the solid state substrate parent. The solid state substrate structure has a structure in which the parylene N and parlylene A thin film are mixing evaporated on the solid state substrate parent and the solid state substrate parent.;COPYRIGHT KIPO 2012
机译:目的:提供一种用于使用固相合成的肽合成的固体底物结构和该固体底物结构的制造方法,即使在固相中也可以合成肽,该固相在反应所需的有机溶剂环境中是易受伤害的。使用固相合成的用于肽合成的固体底物结构包括聚对二甲苯薄膜,其中形成了用于肽合成的固态底物母体和胺自由基衍生物。固态基板结构具有其中在固态基板母体和固态基板母体上蒸发聚对二甲苯N薄膜,并且在聚对二甲苯N薄膜上蒸发聚对二甲苯A薄膜的结构。聚对二甲苯N薄膜的厚度为300纳米以上至1微米以下。固态基板结构具有其中聚对二甲苯薄膜在固态基板母体和固态基板母体上蒸发的结构。固态衬底结构具有其中聚对二甲苯N和聚对二甲苯A薄膜混合蒸发在固态衬底母体和固态衬底母体上的结构。; COPYRIGHT KIPO 2012

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