Composition Comprising Adeno-Associated Virus Serotype 5 Vector for Targeted Gene Delivery

摘要

The present invention, adenovirus comprising a nucleic acid encoding an a targeting motif peptide to the capsid protein internal amino acid residue of the virus vector inserted into the capsid protein sequence-supplied virus serotype 5 targeted recombinant viral vector and the tumor with the vector treatment of the resulting It relates to a composition which comprises a foreign gene inserted into a vector, such as genes and them. By using a recombinant viral vector, the targeting of the present invention may be useful in various diseases such as tumors. ; Recombinant adeno-supplied virus serotype 5 (Recombinant adeno-associated virus serotype 5), capsid formula, directional virus, human cancer cells