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METHOD OF COMBINATION TREATMENT OF LOCALLY ADVANCED NON-SMALL-CELL LUNG CANCER

机译:局部晚期非小细胞肺癌联合治疗方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, oncology, and can be used for combination treatment of locally advanced non-small-cell lung cancer. That is ensured by thorax computed tomography to determine an area of parietal and visceral pleura. It is attended by lung reduction with mediastinal lymph node dissection. That is accompanied with intraoperative photoradiation therapy. It is ensured by intravenous introduction of Photoditasine 0.8-1.0 mg/kg of body weight, In 2 hours, a lymph node dissection region, bronchial and vascular stumps are exposed to light stimuli generated by a diode laser at wave length 662 s and power density 40 J/cm2 for a time estimated on account of the area of the lymph node dissection regions, the bronchial and vascular stumps. It is followed by light stimuli covering the parietal and visceral pleura at power density 4 J/cm2 for a time estimated on account of the area of the bronchial and vascular stumps.;EFFECT: method provides improved therapeutic effects ensured by destruction of the lesions both within the lymph node dissection region, and on the periphery of the lung root reduction and tumour cell resorption in the operative wound, prevention of developing recurrent tumour growth within the pleural cavity.;6 cl, 2 dwg, 3 tbl, 2 ex
机译:领域:药物;发明:本发明是指药物,肿瘤学,并且可以用于局部晚期非小细胞肺癌的联合治疗。这可以通过胸部计算机断层扫描确定顶壁和内脏胸膜的面积来确保。伴有纵隔淋巴结清扫术的肺复位术。伴随着术中光辐射疗法。通过静脉内引入0.8-1.0 mg / kg体重的光达他星来确保这一点。在2小时内,淋巴结清扫区域,支气管和血管残端暴露于由二极管激光器产生的波长为662 s的波长和功率密度的光刺激下。由于淋巴结清扫区域,支气管和血管残端的面积,估计时间为40 J / cm 2 。随后,以功率密度为4 J / cm 2 的方式覆盖壁层和内脏胸膜的光刺激,其时间取决于支气管和血管残端的面积。通过破坏淋巴结清扫区域内的病变以及对术中伤口的肺根减少和肿瘤细胞吸收的破坏确保的效果,防止胸膜腔内复发性肿瘤的发展。6cl,2 dwg ,3 tbl,2 ex

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