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Compositions and methods for treatment and prevention of disease

机译:用于治疗和预防疾病的组合物和方法

摘要

The present invention relates to various novel substituted dipeptide derived nitrogen-containing heterocyclic compounds, their pharmaceutically acceptable salt derivatives, and their methods of use. In one aspect the present invention relates to compositions and methods for the treatment and prevention of disease in a mammal comprising administering the compounds of the invention in a pharmaceutically acceptable form to a mammal. In particular, the invention relates to medicaments comprising various novel substituted dipeptide derived nitrogen- containing heterocyclic compounds and pharmaceutically acceptable salt derivatives and methods for administration to a mammal for the treatment and prevention of malarial diseases. The compounds of the invention may optionally be administered with at least one pharmaceutically acceptable excipient, another biologically active agent or a combination thereof.
机译:本发明涉及各种新颖的取代的二肽衍生的含氮杂环化合物,它们的药学上可接受的盐衍生物及其使用方法。一方面,本发明涉及用于治疗和预防哺乳动物疾病的组合物和方法,其包括将药学上可接受的形式的本发明化合物给予哺乳动物。特别地,本发明涉及包含各种新颖的取代的二肽衍生的含氮杂环化合物和药学上可接受的盐衍生物的药物,以及用于向哺乳动物给药以治疗和预防疟疾的方法。本发明的化合物可任选与至少一种药学上可接受的赋形剂,另一种生物活性剂或其组合一起给药。

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