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Genome-Wide Association Study Identifying Determinants Of Facial Characteristics For Facial Image Generation

机译:全基因组关联研究确定面部特征的面部特征决定因素

摘要

The present invention relates to a method for the generation of a facial composite from the genetic profile of a DNA-donor. The method comprises the steps of a) subjecting a biological sample to genotyping thereby generating a profile of genetic markers associated to numerical facial descriptors (NFD) for said sample, b) reverse engineer a NFD from the profile of the associated genetic variants and constructing a facial composite from the reverse engineered numerical facial descriptors (NFDs). The present invention also relates to a method for identifying genetic markers and/or combinations of genetic markers that are predictive of the facial characteristics, (predictive facial markers) of a person, said method comprising the steps of: a) capturing images of a group of individual faces; b) performing image analysis on facial images of said group of individual faces thereby extracting phenotypical descriptors of the faces; c) obtaining data on genetic variation from said group of individual and d) performing a genome-wide association study (GWAS) to identify said predictive facial markers.
机译:由DNA供体的遗传特征产生面部复合物的方法技术领域本发明涉及一种根据DNA供体的遗传特征产生面部复合物的方法。该方法包括以下步骤:a)对生物样品进行基因分型,从而产生与所述样品的数字面部描述符(NFD)相关的遗传标记的谱图; b)从相关的遗传变体的谱图逆向工程NFD并构建来自逆向工程化数字面部描述符(NFD)的面部合成。本发明还涉及一种用于识别预测人的面部特征的遗传标记和/或遗传标记的组合的方法(预测性面部标记),所述方法包括以下步骤:a)捕获一组图像个人面孔; b)对所述一组单个面部的面部图像进行图像分析,从而提取面部的表型描述符; c)从所述个体的组获得关于遗传变异的数据,和d)进行全基因组关联研究(GWAS)以鉴定所述预测性面部标记。

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