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Methods and related compositions using specific flavonoids and indanes to reduce weight and inhibit lipase, α-amylase and α-glucosidase activity in mammals

机译:使用特定的类黄酮和茚满酮减轻哺乳动物体重并抑制脂肪酶,α-淀粉酶和α-葡萄糖苷酶活性的方法和相关组合物

摘要

The present invention relates generally to methods and related compositions using flavonoids and/or indanes extracted from the stems and leaves of C. quadrangularis to reduce weight and inhibit lipase, α-amylase and α-glucosidase activity in mammals. By example and not by way of limitation, embodiments of the present disclosure, a composition and related methods for reducing body weight and/or inhibiting any combination of lipase, α-amylase and α-glucosidase is provided. The composition contains an effective amount of one or more flavonoids or indanes selected from 3-O-rhamnopyranosylkaempferol, 3-(4-hydroxybenzylidene)-2-(2,5-dihydroxyphenyl)-1-(4-hydroxyphenyl)indane-4,6-diol, quercitrin, rhamnitrin, rhamnocitrin, quercitrin-3-O″-acetate and parthenocissin A.
机译:本发明总体上涉及使用从I C的茎和叶中提取的类黄酮和/或茚满的方法和相关组合物。降低体重并抑制哺乳动物的脂肪酶,α-淀粉酶和α-葡萄糖苷酶活性。通过举例而非限制的方式,提供了本公开的实施方案,用于降低体重和/或抑制脂肪酶,α-淀粉酶和α-葡糖苷酶的任何组合的组合物和相关方法。该组合物包含有效量的一种或多种选自3-O-鼠李吡喃糖基山ka酚,3-(4-羟基亚苄基)-2-(2,5-二羟基苯基)-1-(4-羟基苯基)茚满-4的类黄酮或茚满, 6-二醇,槲皮素,鼠李糖苷,鼠李糖胞苷,槲皮素-3-O''-乙酸盐和单性菊红素A。

著录项

  • 公开/公告号US8362090B2

    专利类型

  • 公开/公告日2013-01-29

    原文格式PDF

  • 申请/专利权人 JULIUS ENYONG OBEN;

    申请/专利号US20100685990

  • 发明设计人 JULIUS ENYONG OBEN;

    申请日2010-01-12

  • 分类号A01N31;A01N59;A61K31/045;A61K33;C09B31;C09B33;C09B35;C09B37;

  • 国家 US

  • 入库时间 2022-08-21 16:43:27

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