Method to identify a population of TR1 cells at Rest, which involves the detection of the expression of cell surface markers CD4, CD25,Disorders and CD62L; isolated population of TR1 cells; method to decrease a population of TR1 cells; Kit for identifying or Isolating a population of TR1 cells at rest and / or activated; fa compositionRmaceutica comprising a population of TR1 cells at rest and / or activated.

摘要

The present invention relates to methods for isolating Tr1 cells, resting Tr1 cells and/or activated Tr1 cells, to methods for enriching or depleting a cell population in Tr1 cells, resting Tr1 cells and/or activated Tr1 cells and to methods and kits for treating chronic inflammatory diseases, autoimmune diseases, allergic diseases, cancer and organ transplantation conditions.