Use of a hydroalcoholic extract of Ruta graveolens and / or Antihypertensive and Vasodilator agent; Preparation method of a hydroalcoholic extract of Ruta graveolens.

摘要

The invention relates to the use of a hydroalcoholic plant extract obtained from the Ruta graveolens species in order to prevent and/or treat arterial hypertension, as it exhibits a marked vasodilator effect in vitro and anti-hypertensive effect in vivo, the latter being verified by orally administering the extract to rats in which a hypertensive level has been induced. The extract is orally administered in a lyophilized manner, either in a capsule or directly dissolved in water, with a mainly preventive purpose, but also as a therapeutic agent for the hypertensive level, as there are currently no monotherapies that have an adequate cost-effectiveness ratio. Although there are various types of drugs that are usually used in the treatment of this disease, the efficiency thereof is not adequate and they normally have to be combined, potentially presenting undesirable side effects.