Insect-based model for studying the effect of nanoparticles on the blood-brain barrier function and integrity

摘要

There is provided a method and model insects for screening the effects of nanoparticles on brain barrier function and integrity.The method involves exposing the insect brain barrier to the nanoparticle(s) of interest and exposing the nanoparticle treated insect brain barrier to one or more suitable marker(s) of the function and integrity of the brain barrier.