Method of classification of non small cell lung carcinoma based on the identification of an intratumoral immune response.

摘要

Classification method nonsmall cell lung based on the identification of intratumoral immune response. # The present invention relates to an in vitro method of classification nonsmall cell lung based on differential expression of 50 genes. Such genes identified intratumoral immune response. By the method of the invention differ patients with an expression profile of genes associated with an immune response that is associated with good prognosis and patients without the expression profile poorest prognosis. This classification can be used as a prognostic marker as tumors classifier based on the antitumor immune response (? Inmunoscore?) Or as a biomarker predictor based on the immune system (immunotherapy) therapies. The present invention also relates to a kit comprising a set of probes that recognize the 50 genes of the invention.