Methods and apparatus for manipulating droplets by electrowetting- based techniques

摘要

#$%^&*AU2010201422C120130926.pdf#####180/155 PCT Abstract of the Disclosure An apparatus is provided for manipulating droplets. The apparatus is a single-sided electrode design in which all conductive elements are contained on one surface on which droplets are manipulated. An additional surface can 5 be provided parallel with the first surface for the purpose of containing the droplets to be manipulated. Droplets are manipulated by performing electrowetting-based techniques in which electrodes contained on or embedded in the first surface are sequentially energized and de-energized in a controlled manner. The apparatus enables a number of droplet manipulation 10 processes, including merging and mixing two droplets together, splitting a droplet into two or more droplets, sampling a continuous liquid flow by forming from the flow individually controllable droplets, and iterative binary or digital mixing of droplets to obtain a desired mixing ratio. A method of sampling a continuous liquid flow is also provided. 151/40 Cl C2 I C3 10 25 G V 2 L S2 ___ S3 Fig. 1