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FIBRINOGENOLYTIC ENZYME TABFIBLYSIN OF HORSEFLY, TABANUS YAO, ENCODING GENE AND USE THEREOF
FIBRINOGENOLYTIC ENZYME TABFIBLYSIN OF HORSEFLY, TABANUS YAO, ENCODING GENE AND USE THEREOF
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机译:麻,塔巴努斯纤维蛋白原酶TABABILS,编码基因及其用途
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摘要
A horsefly protease tabfiblysin isolated from the salivary gland of the horsefly, Tabanus Yao, a gene encoding the protease and use thereof are disclosed by the present invention. It belongs to the technical field of biomedicine. The molecular weight of the horsefly protease tabfiblysin is 27145.5 Daltons. Its full-length sequence is composed of 255 amino acids. Its encoding sequence is composed of 768 nucleotides. The horsefly protease tabfiblysin can hydrolyze fibrinogen and inhibit the aggregation of blood platelet dramatically, and can be used for preparing the drug for treating thrombotic diseases.
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