首页> 外国专利> BIODEGRADABLE POLY PARA-DIOXANONE LIGATURE, METHOD FOR MANUFACTURING THE LIGATURE, KIT DEVICE USING THE LIGATURE AND METHOD FOR USING THE KIT DEVICE

BIODEGRADABLE POLY PARA-DIOXANONE LIGATURE, METHOD FOR MANUFACTURING THE LIGATURE, KIT DEVICE USING THE LIGATURE AND METHOD FOR USING THE KIT DEVICE

机译:生物可降解的聚对二恶烷酮系带,制造该系带的方法,使用该系带的套件设备以及该套件设备的使用方法

摘要

Disclosed are a biodegradable poly para-dioxanone ligature, a method for manufacturing the ligature, a kit device using the ligature and a method for using the kit device. The present invention relates to a manufacturing method comprising: a step (S1) of crystallizing para-dioxanone generated from a dehydration reduction of diethylene glycol and performing a distillation at the vacuum condition of 10-4 to 10-2 torr; a step (S2) of stirring the para-dioxanone and at least one selected from a group consisting of caprolactone, trimethylene carbonate and glycolide and polyethylene glycol so as to prepare poly para-dioxanone; a step (S3) of drying the poly para-dioxanone to prepare a thread having a diameter of 50 to 100 µm; and a step (S4) of stretching the thread at an elongation of 5 to 10 times using an infrared ray source. The present invention also relates to a biodegradable poly para-dioxanone ligature manufactured by the method, a kit device using the ligature and to a method for using the kit device. Thus, it is possible to prepare poly para-dioxanone suitable for biocompatibility of a mammal from high purity para-dioxanone. When the thus-prepared poly para-dioxanone is implanted between the true skin and the panniculus of a mammal, the poly para-dioxanone may cause stimulation and generation of the skin fibroblast to improve wrinkles and cause skin volume to expand, thereby achieving the effects of plastic surgery.
机译:公开了可生物降解的聚对二恶烷酮连接物,该连接物的制造方法,使用该连接物的试剂盒装置以及该试剂盒装置的使用方法。本发明涉及一种制造方法,其包括使由二甘醇脱水还原而产生的对二恶烷酮结晶并在真空度为10 -4 至10 的条件下进行蒸馏的步骤(S1)。 Sup> -2 torr;步骤(S2),将对二恶烷酮与选自己内酯,碳酸三亚甲基酯,乙交酯和聚乙二醇中的至少一种进行搅拌以制备聚对二恶烷酮。干燥聚对二恶烷酮以制备直径为50至100μm的线的步骤(S3);步骤(S4),使用红外线源以5〜10倍的伸长率拉伸线。本发明还涉及通过该方法制造的可生物降解的聚对二恶烷酮连接物,使用该连接物的试剂盒装置以及使用该试剂盒装置的方法。因此,可以由高纯度的对二恶烷酮制备适合哺乳动物的生物相容性的聚对二恶烷酮。当将如此制备的聚对二恶烷酮植入哺乳动物的真实皮肤与睑板之间时,聚对二恶烷酮可刺激并生成皮肤成纤维细胞以改善皱纹并引起皮肤体积扩大,从而达到效果。整形外科。

著录项

  • 公开/公告号WO2013094994A1

    专利类型

  • 公开/公告日2013-06-27

    原文格式PDF

  • 申请/专利权人 KIM HYOUNG JIN;HAN DONG HEE;

    申请/专利号WO2012KR11146

  • 发明设计人 KIM HYOUNG JIN;HAN DONG HEE;

    申请日2012-12-20

  • 分类号A61L17/10;A61L17;

  • 国家 WO

  • 入库时间 2022-08-21 16:32:14

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号