首页> 外国专利> IMPLANT OR SCAFFOLD WHICH IMPROVES OSSEOINTEGRATION AND RELEASES ANTIBIOTICS AND OSTEOGENESIS-PROMOTING MATERIALS AND A METHOD FOR MANUFACTURING THE SAME

IMPLANT OR SCAFFOLD WHICH IMPROVES OSSEOINTEGRATION AND RELEASES ANTIBIOTICS AND OSTEOGENESIS-PROMOTING MATERIALS AND A METHOD FOR MANUFACTURING THE SAME

机译:植入物或脚手架,其可促进骨整合并释放出抗菌剂和成骨促进材料及其制造方法

摘要

PURPOSE: An implant or a scaffold is provided to prevent attachment, growth, and infection of bacteria remarkably reducing the rate of failure for an implant or a scaffold plantation.;CONSTITUTION: An implant or a scaffold has the surface which is modified using complex compounds containing a polymer-catechol functional group. The implant or scaffold contains one or more kinds of materials selected among antibiotics and osteogenesis-promoting materials. A method for manufacturing the implant or the scaffold comprises the steps of: preparing the complex; modifying and activating the surface of the implant or the scaffold using the complex; dipping the implant or the scaffold into an antibiotics-containing solution and stirring the solution at 20-25°C for 4-24 hours to fix the antibiotics on the surface of the implant or the scaffold; and dipping the implant or the scaffold into a solution containing the osteogenesis-promoting materials and stirring the solution at 20-25°C for 4-24 hours to fix the osteogenesis-promoting materials on the surface of the implant or the scaffold.;COPYRIGHT KIPO 2013;[Reference numerals] (AA) Heparin-dopamine; (BB) Gentamycin; (CC) Heparin-fixed titanium; (DD) Gentamycin/heparin-titanium; (EE) Gentamycin/BMP-2/heparin-titanium
机译:目的:提供植入物或支架,以防止细菌的附着,生长和感染,从而显着降低植入物或支架种植的失败率。;组成:植入物或支架的表面经过复杂化合物的修饰含有聚合物邻苯二酚官能团。植入物或支架包含选自抗生素和成骨促进材料中的一种或多种材料。一种用于制造植入物或支架的方法,包括以下步骤:制备复合物;以及使用复合物修饰和激活植入物或支架的表面;将植入物或支架浸入含抗生素的溶液中,并在20-25℃下搅拌4-24小时,以将抗生素固定在植入物或支架的表面上;将植入物或支架浸入含有促进骨形成的材料的溶液中,并在20-25℃下搅拌4-24小时,以将促进骨形成的材料固定在植入物或支架的表面上。 KIPO 2013; [参考数字](AA)肝素-多巴胺; (BB)庆大霉素; (CC)肝素固定钛; (DD)庆大霉素/肝素钛; (EE)庆大霉素/ BMP-2 /肝素钛

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