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IMPLANT OR SCAFFOLD WHICH IMPROVES OSSEOINTEGRATION AND RELEASES ANTIBIOTICS AND OSTEOGENESIS-PROMOTING MATERIALS AND A METHOD FOR MANUFACTURING THE SAME
IMPLANT OR SCAFFOLD WHICH IMPROVES OSSEOINTEGRATION AND RELEASES ANTIBIOTICS AND OSTEOGENESIS-PROMOTING MATERIALS AND A METHOD FOR MANUFACTURING THE SAME
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机译:植入物或脚手架,其可促进骨整合并释放出抗菌剂和成骨促进材料及其制造方法
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PURPOSE: An implant or a scaffold is provided to prevent attachment, growth, and infection of bacteria remarkably reducing the rate of failure for an implant or a scaffold plantation.;CONSTITUTION: An implant or a scaffold has the surface which is modified using complex compounds containing a polymer-catechol functional group. The implant or scaffold contains one or more kinds of materials selected among antibiotics and osteogenesis-promoting materials. A method for manufacturing the implant or the scaffold comprises the steps of: preparing the complex; modifying and activating the surface of the implant or the scaffold using the complex; dipping the implant or the scaffold into an antibiotics-containing solution and stirring the solution at 20-25°C for 4-24 hours to fix the antibiotics on the surface of the implant or the scaffold; and dipping the implant or the scaffold into a solution containing the osteogenesis-promoting materials and stirring the solution at 20-25°C for 4-24 hours to fix the osteogenesis-promoting materials on the surface of the implant or the scaffold.;COPYRIGHT KIPO 2013;[Reference numerals] (AA) Heparin-dopamine; (BB) Gentamycin; (CC) Heparin-fixed titanium; (DD) Gentamycin/heparin-titanium; (EE) Gentamycin/BMP-2/heparin-titanium
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