Compositions for Preventing, Ameliorating, or Treating Symptom of Atopic Dermatitis

摘要

The present invention relates to a composition for the prevention, improvement or treatment of atopic dermatitis comprising rover oak bark extract, Centella asiatica extract, Echochocho extract, plum extract and green tea extract as active ingredients. The active ingredient included in the composition of the present invention is reduced blood levels of IgE in the induced inflammation model, inhibits tissue penetration of cells expressing inflammatory proteins such as neutrophil cells, T cells and iNOS, decreases the expression of phosphorylated STAT3 and cytokeratin 1 Through molecular mechanisms, such as to mitigate abnormal thickening of skin tissues through the excellent atopic dermatitis symptoms have the effect of preventing, improving or treating. In addition, the composition of the present invention can be safely applied to cosmetics, pharmaceutical and food compositions because there is no cytotoxic and skin side effects.