Dental implant materials surface-modified with supramolecular polyrotaxane structure

摘要

The present invention release bioactive substances such as growth factors or osteoinductive capability drugs after implantation in the human body and relates to an implant material and a method of manufacturing the dental modified by supramolecular structures in poly taxane in promoting osseointegration and improve the therapeutic effect. Dental implant material according to the invention, which can be implanted into the body implant base, which is chemically bonded to the polyester surface of the implant base to taxanes, including the poly a bioactive substance chemically bound to the taxane to be hydrolyzed, and wherein polyacrylic acid is suspended in a biocompatible polymer and a biocompatible linear cyclic linear molecule and the cyclic molecule is sandwiched by the polymer molecules having a chemical bonding that is capped on both ends to allow hydrolysis of the biocompatible polymer so as not to deviate from a linear biocompatible polymer linear The. To the dental implant material according to the invention is equipped with a bioactive substance, such as growth factors or osteoinductive capacity to taxane drug is chemically bonded to the polyester to be hydrolyzed by enzymes or pH in the body to the surface of the base implant, implant promote osseointegration of the region and enhances the therapeutic effect. ;