ADJUSTMENT OF THE AMINO ACID POOL NECESSARY FOR SYNTHESIS OF ACUTE PHASE PROTEINS

摘要

1. The combination of (i) serine, (ii) cysteine, (iii) arginine, and (iv) at least one branched chain amino acid for use in the therapeutic or prophylactic treatment of inflammation or infection, the combination being administered enterally as well as the combination forms part of a nutritional composition having a glycemic index below 55.2. The combination according to claim 1 for use in the therapeutic or prophylactic treatment of an imbalance in the metabolic use of amino acids from body or food resources in a subject with inflammation or infection, the combination being administered enterally and the combination also forms part of a nutritional composition having a glycemic index below 55.3. The combination according to claim 2, wherein the therapeutic or prophylactic treatment is the treatment of an imbalance in the metabolic use of amino acids from body or food resources for the synthesis of acute phase proteins. The combination according to claim 1, wherein the combination is part of a nutritional composition having a glycemic index ranging from 0-45.5. The combination according to claim 1, further comprising (v) at least one component selected from the group consisting of phenylalanine, threonine, tryptophan, methionine and lysine, preferably containing each of these components. The combination according to claim 5, in which the total relative amount of branched chain amino acids in weight percent of the total amount of leucine, isoleucine, valine, phenylalanine, threonine, tryptophan, methionine and lysine is in the range of 45-75 wt.%, In particular in the range 55-65 wt.%. 7. The combination according to claim 1, containing a nutritional anti-inflammatory component. The combination of claim 7, wherein