AGENT IMPROVING CARDIAC RESISTANCE TO ISCHEMIC AND FOLLOWING REPERFUSION INJURIES

摘要

FIELD: medicine.;SUBSTANCE: what is presented is the preventive use of an opioid receptor blocker 'CTAP' as an agent improving the cardiac resistance to ischemic and following reperfusion injuries. What is shown is an ability of 'CTAP' to prevent the above injuries (to reduce a necrosis area and a risk area) when introduced 25 min before the 30-minute coronary occlusion and the following 3-hour reperfusion.;EFFECT: invention may be used for creating the new effective agent improving the cardiac resistance to ischemic and following reperfusion injuries.;2 tbl