NOVEL TOP USE, COSMETIC OR DERMOPHARMACEUTICAL, OF A MIXTURE COMPRISING A GHK TYPE TRIPEPTIDE AND A GQPR TYPE TETRAPEPTIDE

摘要

According to the invention, a mixture of A-GHK-B tripeptide and A-GQPR-B tetrapeptide (SEQ ID NO: 1), or their derivatives or analogs, for the therapeutical treatment of the papillary dermis, with: A = H, CO-R1, SO2-R1; B = OH, OR1, NH2, NHR1, NR1R2; R1 and R2 being, independently of one another, selected from an alkyl, aryl, aralkyl, alkylaryl, alkoxy and aryloxy group, which may be linear, branched, cyclic, polycyclic, unsaturated, hydroxylated, carbonylated, phosphorylated and/or sulfured, said group which may have a heteroatom in its skeleton including O, S and/or N; is used to prevent damage to the papillary dermis and/or repair the dermis papillary, to prevent and/or treat skin aging, in particular photo-induced aging.