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Dendrimer compounds, dendrimer complexes and MRI contrast agents

机译:树枝状化合物,树枝状复合物和MRI造影剂

摘要

A core of a cyclic structure represented by (N(CH2)n)k is bonded to a dendrimer-type side chain with a specific branched structure at all nitrogen atoms in the core to produce a compound with a specific structure for producing a metal complex that exhibits a T1-reducing effect, and the resulting compound is coordinated to a metal ion that has a T1-reducing effect to obtain a metal complex that exhibits an excellent T1-reducing effect which is useful as an effective component of an MRI contrast agent and an MRI contrast agent using the same.
机译:以(N(CH 2)n)k表示的环状结构的核键合到在核中所有氮原子上具有特定支化结构的树枝状聚合物型侧链上,从而生成具有特定结构的化合物,该化合物用于制备金属络合物表现出T1还原作用的化合物,将得到的化合物与具有T1还原作用的金属离子配位,从而获得表现出优异的T1还原作用的金属络合物,该金属络合物可用作MRI造影剂的有效成分。并使用MRI造影剂。

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