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METHOD OF DETERMINING HOMOZYGOTE AND HETEROZYGOTE

机译:测定纯合子和杂合子的方法

摘要

In order to accurately determine a homozygote and a heterozygote in a melting curve analysis, provided is an apparatus for detecting a signal from a specimen, the apparatus including a fluidic device including: a fluid path through which the specimen is passable; a reaction unit provided in the fluid path; a heater configured to elevate a temperature of the specimen in the reaction unit so as to perform the melting curve analysis; and a heater driving unit configured to drive the heater. The heater driving unit is configured to drive the heater at a first temperature elevation rate that is equal to or higher than 1° C./s and a second temperature elevation rate that is different from the first temperature elevation rate so that the fluidic device performs multiple times of the melting curve analysis for specimens including the same component.
机译:为了在熔解曲线分析中准确地确定纯合子和杂合子,提供了一种用于检测来自样本的信号的设备,该设备包括流体装置,该流体装置包括:样本可通过的流体路径;设置在流体路径中的反应单元;加热器,其被配置为升高反应单元中样本的温度,以进行熔解曲线分析;加热器驱动单元,其被配置为驱动加热器。加热器驱动单元被配置为以等于或高于1℃/ s的第一温度升高速率和不同于第一温度升高速率的第二温度升高速率驱动加热器,从而流体装置执行对包含相同成分的样品进行多次熔解曲线分析。

著录项

  • 公开/公告号US2014038189A1

    专利类型

  • 公开/公告日2014-02-06

    原文格式PDF

  • 申请/专利权人 CANON KABUSHIKI KAISHA;

    申请/专利号US201313950563

  • 发明设计人 EISHI IGATA;

    申请日2013-07-25

  • 分类号C12Q1/68;

  • 国家 US

  • 入库时间 2022-08-21 16:01:29

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