Pulsed ASL using tagging pulse pattern encoding/decoding of flowing nuclei cohorts

摘要

Magnetic resonance imaging (MRI) produces an image representative of flowing nuclei within a subject. For each of plural MRI data acquisition sequences, a non-contrast pulsed ASL (arterial spin labeling) pre-sequence is applied to flowing nuclei in a tagging region during a tagging period (that occurs prior to MRI data acquisition from a selected downstream image region). The ASL pre-sequence includes plural different elapsed tagging times at which a radio frequency (RF) nuclear magnetic resonant (NMR) nutation tagging pulse occurs or does not occur in accordance with different predetermined patterns for corresponding different data acquisition sequences. Acquired MRI data is decoded in accordance with such predetermined patterns to detect MRI signals emanating from different cohorts of flowing nuclei that have been subjected to different combinations of nutation pulses. Acquired MRI data is used to reconstruct at least one image representing flowing nuclei within the selected image region.