Recovery process of nalmefene hydrochloride from an aqueous composition containing Naltrexone and nalmefene hydrochloride, which comprises the step of Isolate nalmefene HCl from an aqueous suspension comprene bisulfite Adduct of Naltrexone and nalmefene HCl Solid.

摘要

The present invention relates to an improved process for recovery of nalmefene hydrochloride[17-(cyclopropylmethyl)-4,5-alpha-epoxy-6-methylenemorphinan-3,14-diol hydrochloride] from an aqueous composition containing nalmefene and certain impurities.