首页> 外国专利> COMPOSITION COMPRISING A FIBRONECTIN BINDING PROTEIN OR A FIBRONECTIN BINDING PEPTIDE

COMPOSITION COMPRISING A FIBRONECTIN BINDING PROTEIN OR A FIBRONECTIN BINDING PEPTIDE

机译:包含纤连蛋白结合蛋白或纤连蛋白结合肽的组合物

摘要

The present invention relates to a composition comprising at least one fibronectin binding protein, and/or at least one a truncated fibronectin binding protein and/or at least one fibronectin binding peptide, all comprising at least one fibronectin binding domain; and at least one iscom matrix complex and/or liposome and/or at least one lipid and at least one saponin, whereby the at least one lipid and the at least one saponin may be in complex, solution or suspension. Further, it regards use thereof for the preparation of a vaccine against a micro organism that comprises at least one fibronectin binding domain. It also relates to a kit of parts comprising at least two compartments, wherein one compartment comprises at least one truncated fi-bronectin binding protein and/or a fibronectin binding peptide, that comprises at least one fibronectin binding domain, and another compartment comprises an instruction for use and/or an iscom matrix complex and/or an iscom complex and or a liposome. Further it relates to a method for vaccination of an individual.
机译:本发明涉及一种组合物,其包含至少一种纤连蛋白结合蛋白和/或至少一种截短的纤连蛋白结合蛋白和/或至少一种纤连蛋白结合肽,均包含至少一个纤连蛋白结合结构域;至少一种iscom基质复合物和/或脂质体和/或至少一种脂质和至少一种皂苷,其中所述至少一种脂质和所述至少一种皂苷可以为复合物,溶液或悬浮液。此外,本发明涉及其在制备针对包含至少一个纤连蛋白结合域的微生物的疫苗中的用途。它还涉及包含至少两个区室的零件套件,其中一个区室包含至少一个截短的纤连蛋白结合蛋白和/或纤连蛋白结合肽,其包含至少一个纤连蛋白结合域,而另一个区室包含说明使用和/或iscom基质复合物和/或iscom复合物和/或脂质体。此外,本发明涉及一种用于个体接种的方法。

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