New amide derivatives of mycophenolic acid, the process for preparing amide derivatives of mycophenolic acid, and the use of new amide derivatives of mycophenolic acid for the manufacture of an immunosuppressant in particular reducing the risk of transplant rejection
the subject of the invention are new derivatives of mycophenolic acid amide linkages of general formula 2, where r is h or ch3, or ch2ph or ch (ch3) 2, or ch2ch (ch3) 2, or ch2ch2cooh or ch (oh) ch3, or (ch2) 3nh (c = nh) nh2, r means ch3 or h. the subject invention are also ways otrzymywa nia linkages derived of mycophenolic acid with the general formula 2.the invention also includes the use of new linkages derived of mycophenolic acid with the general formula 2, where r is h or ch3, or ch2ph or ch (ch3) 2, ch2ch (ch3) 2 or ch2ch2cooh or ch (oh) ch3, or (ch2) 3nh (c = nh) nh2, r is ch3 or h for the manufacture of immunosuppressant. especially at risk of transplant rejection.
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