A PROCESS FOR THE PALLADIUM-CATALYZED COUPLING OF TERMINAL ALKYNES WITH HETEROAYL TOSYLATES AND HETEROARYL BENZENESULFONATES

摘要

THE PRESENT INVENTION RELATES TO A PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF COMPOUNDS OF THE FORMULA (I). WHEREIN D, J AND W HAVE THE MEANINGS INDICATED IN THE CLAIMS. THE PRESENT INVENTION PROVIDES AN EFFICIENT AND GENERAL PALLADIUM CATALYZED COUPLING PROCESS OF HETEROARYL TOSYLATES WITH TERMINAL ALKYNES TO A WIDE VARIETY OF SUBSTITUTED, MULTIFUNCTIONAL HETEROARYL-1 -ALKYNES OF THE FORMULA I USEFUL FOR THE PRODUCTION OF PHARMACEUTICALS, DIAGNOSTIC AGENTS, LIQUID CRYSTALS, POLYMERS, HERBICIDES, FUNGICIDALS, NEMATICIDALS, PARASITICIDES, INSECTICIDES, ACARICIDES AND ARTHROPODICIDES.