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Using the miR-26 family as a predictive marker of hepatocellular carcinoma and sensitivity to therapy

机译:使用miR-26家族作为肝细胞癌和对治疗敏感性的预测指标

摘要

A method for predicting clinical outcome of a patient who has been diagnosed hepatocellular carcinoma (HCC) comprising detecting the expression level of miR-26 in a sample of HCC tumor that haobtenido patient, wherein a decrease in 1.5 times or more the expression level of miR-26 in lamuestra tumor relative to a control predicts a decrease in survival, predicts respuestafavorable to therapy with interferon (IFN) -a, or both, in the the clinical outcome is a respuestafavorable to interferon therapy.
机译:一种用于预测已被诊断为肝细胞癌(HCC)的患者的临床结局的方法,该方法包括检测hatentenido患者的HCC肿瘤样品中miR-26的表达水平,其中miR的表达水平降低1.5倍或更多倍相对于对照,lamuestra肿瘤中的-26预测存活率降低,预测对干扰素(IFN)-a的治疗有利,或两者兼有,在临床结果中对干扰素治疗有利。

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