New variants of E1 envelope protein of rubella and their use in detecting anti-rubella antibodies

摘要

Rubella E1 antigen comprising amino acids 201 to 432, with the proviso that said present antígenono sequences corresponding to amino acids 143-164 and 454-481 of the E1 antigen rubéolanativo and contains two disulfide bridges, which is formed a disulfide bond between Cys 225 and Cys 235 (C13-C14) and a second disulfide bridge between Cys 349 and Cys 352 (C17-C18) is formed.